FLORCRID 100 mg/ml

100 mg/ml, oral solution for pigs and chickens (broilers)

Indications

Pigs

Treatment and metaphylaxis at the group level where clinical signs are present of swine respiratory disease associated with Actinobacillus pleuropneumoniae and Pasteurella multocida.

Chickens (broilers)

Treatment and metaphylaxis at the group level where clinical signs are present of:

-    Enteritis (colibacillosis) caused by E.coli.

-    Respiratory disease (mycoplasmosis) caused by Mycoplasma  gallisepticum.

 

CONTRAINDICATIONS

Do not use in the case of known hypersensitivity to the active substance or to excipient.

Do not use in boars intended for breeding purposes.

COMPOSITION

Florfenicol         100 mg/ml

 

ADVERSE REACTIONS

In pigs, a reduction in water intake and the following adverse reactions may occur during treatment: perianal and rectal erythema/edema, transient diarrhea, constipation with dark brown feces.

These reactions are transient and reversible.

 

DOSAGE FOR EACH SPECIES, ROUTES AND METHOD OF ADMINISTRATION

Administration: orally via drinking water.

Pigs: 10 mg florfenicol/kg b.w./day, for 5 days respectively 0.10 ml product Florcrid/ kg b.w./ day.

The Amount of Florcrid Solution (AFS) can be calculated based on total body weight of herd to be treated (TBW) and the total water consumption of the herd in 24 hours (TWC) using formula:

 

CSF (L) = 15 x GCT (kg) 100 x CAT (L)

per 1000 liters of water

 

10 = dose / kg b.w.

100 = mg florfenicol/ 1 ml Florcrid

 

Chickens (broilers): 30 mg florfenicol/ kg b.w./day, for 3 days respectively 0.30 ml product Florcrid /kg b.w./ day.

The Amount of Florcrid Solution (AFS) can be calculated based on total body weight of herd to be treated (TBW) and the total water consumption of the herd in 24 hours (TWC) using formula:

 

CSF (L) = 30 x GCT (kg) 100 x CAT (L)

per 1000 liters of water

 

30 = dose / kg b.w.

100 = mg florfenicol/1 ml Florcrid

 

ADVICE ON CORRECT ADMINISTRATION

To ensure correct dosage, body weight should be determined as accurately as possible to avoid underdosing. The uptake of medicated water is dependant on the clinical condition of animals. In order to obtain the correct dosage, the concentration in drinking water may have to be adjusted. In case of insufficient intake of medicated water treatment plan should be revised.

Medicated water should be the only source of drinking water. Medicated drinking water should be prepared fresh every 24 hours.

If there are no signs of improvement during the treatment, the diagnosis should be reviewed and, if necessary, the treatment changed.

WARNING!!!

If using a dosing device, to avoid precipitating of the product, do not use more than 1 liter of product per 100 liters of water. Do not set the dosing device below 2 %.

 

WITHDRAWAL PERIODS

Pigs (meat and offal): 17 days.

Chickens (broilers) (meat and offal): 3 days.

Do not use in birds producing eggs for human consumption.

 

SPECIAL STORAGE PRECAUTIONS

Keep out of sight and reach of children. Store below 25°C. Do not refrigerate or freeze. Store in a dry place. Protect from direct light. Do not use after expiry date which is stated on the label.

 

SHELF-LIFE

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.

Shelf life after first opening the immediate packaging: 28 days.  

Shelf life after reconstitution into drinking water: 24 h.

 

SPECIAL WARNINGS

Special precautions for use in animals

Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local epidemiological (region, farm level) information about susceptibility of the target bacteria. Official, national and regional antimicrobial policies will be considered when using the product.

Use of the product deviating from the instructions in the SPC may increase the risk of development and selection of florfenicol-resistant bacteria and decrease the effectiveness of treatment with other amphenicols due to the potential for cross-resistance.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

This product may cause hypersensitivity reactions.

Do not use the product in known cases of sensitivity to active substance or excipients. People with known hypersensitivity to florfenicol should avoid contact with the veterinary medicinal product. Wear protective gloves or clothing when handling or mixing this product. If you experience symptoms after exposure, such as rash, seek medical advice immediately and show the package leaflet or the label to the physician. This product may be slightly irritating to eyes and / or skin. Wear goggles.

In case of accidental contact with eyes, rinse immediately with plenty of water. In case of accidental skin contact, wash affected area with soap and water and remove contaminated clothing.

Wash hands after use.

In the case of accidental ingestion, wash out mouth immediately with water, seek medical advice and show the leaflet or the label to the physician.

Do not eat, drink or smoke when handling this product or during administering the product to animals.

Use during pregnancy, lactation or lay

Laboratory studies in animals have not produced any evidence of potential embryotoxic or foetotoxic effects. However, the effect of florfenicol to reproductive performance and pregnancy, in target species, has not been assessed. Use only accordingly to the benefit/risk assessment by the responsible veterinarian.

Interactions with other medicinal products and other forms of interaction

No data available.

Overdose

In case of overdosing, a decrease in weight gain, food and water consumption, peri-anal erythema and oedema and modification of some haematological and biochemical parameters indicative of dehydration may be observed.

Major incompatibilities

In the absence of compatibility studies, this veterinary medicinal product should not be mixed with other veterinary medicinal products.

 

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS DERIVED FROM THE USE OF SUCH PRODUCTS, IF APPROPRIATE

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with national requirements. Medicines should not be disposed of via wastewater or household waste. Ask your veterinary surgeon or pharmacist how to dispose of medicines no longer required. Manure from treated animals should not be spread on the same field in successive years.

 

PRESENTATION/PACKAGE

HDPE containers  of 50 ml, 100 ml, 250 ml, 500 ml, 1000 ml, 5, 10 and 20 liters.


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