CLAMOX RTU

140 mg/35 mg/ml, injectable suspension for cattle, pigs, dogs and cats

Indications

The product is indicated for cattle, pigs, dogs and cats for the treatment of the following diseases caused by bacteria susceptible to the action of active substances:

Cattle: respiratory infections, soft tissue infections (abscesses, arthritis), metritis, mastitis.

Pigs: respiratory infections, colibacillosis, periparturial infections in sows (MMA syndrome).

Dogs, cats: urinary tract infections, respiratory tract infections, skin and soft tissue infections (abscesses, pyoderma, perianal gland abscesses, gingivitis).

COMPOSITION

Amoxicillin (as amoxicillin trihydrate)    140 mg /ml

Clavulanic acid (as potassium clavulanate) 35 mg/ml

 

CONTRAINDICATIONS

Do not use in case of hypersensitivity to the active substances or to any of the excipients.

The product should not be administered to rabbits, guinea pigs and hamsters. It should be used with caution in other small herbivores.

 

ADVERSE REACTIONS

Occasionally, the product may cause inoculation site reactions and / or local tissue reactions.

If you notice any side effects, even those not already listed in this package leaflet or you think that the medicine has not worked, please inform your veterinary surgeon.

DOSAGE FOR EACH SPECIES, ROUTES AND METHOD OF ADMINISTRATION

The product may be administered by subcutaneously or intramuscularly route in dogs and cats and only by intramuscularly route in cattle and pigs.

The dose is 8.75 mg active substance / kg body weight, equivalent to 1 ml product / 20 kg body weight, repeated every 24 hours for 3 to 5 consecutive days.

Combination therapy for the treatment of mastitis in cattle: if necessary, CLAMOX RTU can be used in combination with CLAMOX LC.

 

For combined therapy, the following minimum treatment regime should be followed:

CLAMOX RTU

CLAMOX LC

8.75 mg/kg b.w (7.0 mg amoxicillin, 1.75 mg clavulanic acid) i.e. 1 ml / 20 kg b.w

24 hours

One syringe for each quarter affected

8.75 mg/kg b.w. (7.0 mg amoxicillin, 1.75 mg clavulanic acid) i.e. 1 ml / 20 kg b.w.

24 hours

One syringe for each quarter affected

8.75 mg/kg b.w. (7.0 mg amoxicillin, 1.75 mg clavulanic acid) i.e. 1 ml / 20 kg b.w.

When necessary, CLAMOX RTU may be administered for an additional 2 days for a total injectable treatment duration of 5 days.

One syringe for each quarter affected

To ensure correct dosing and to avoid under or overdose, the body weight of the animals should be determined as accurately as possible.

 

ADVICE ON CORRECT ADMINISTRATION

Shake the vial well before use. After injection, massage the injection site. Use a completely dry needle and syringe.

 

WITHDRAWAL PERIODS

Cattle (meat and offal): 42 days.

Milk: 60 hours.

Pigs (meat and offal): 31 days.

In the case of combination therapy, the milk will be given for human consumption 60 hours after the last treatment (after 5 milkings if the cows are milked twice a day).

 

SPECIAL STORAGE PRECAUTIONS

Do not store above 25oC.

Protected from light.

Do not refrigerate.

 

SHELF-LIFE

Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.

Shelf-life after first opening the immediate packaging: 28 days.

 

SPECIAL WARNINGS

Special warnings for each target species

None.

Special precautions for use

Special precautions for use in animals

The use of the product should be based on testing the susceptibility of bacteria isolated from animals. If this is not possible, therapy should be based on epidemiological information about the susceptibility of the target bacteria.

Official, national and regional antimicrobial policies must be observed when using the product.

Use of the product deviating from the instructions in the SPC may increase the risk of development and selection of amoxicillin-resistant bacteria and decrease the effectiveness of treatment with other penicillins due to the potential for cross-resistance.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Penicillins and cephalosporins can cause hypersensitivity reactions (allergies) after self-injection, inhalation, ingestion or skin contact.

Hypersensitivity to penicillins may be associated with cross-sensitivity to cephalosporins and vice versa.

Occasionally, allergic reactions to these substances can be severe.

In case of accidental self-injection, seek medical advice and show the package leaflet or the label to the physician.

In case of accidental skin contact, wash with soap and water. Handle this product with care to prevent exposure by taking all precautions.

This product will not be handled if you know that you are a sensitive person or have been warned not to handle such products.

If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips, or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.

The use during pregnancy, lactation

The product can be used in pregnant animals or during lactation.

Interactions with other medicinal products and other forms of interaction

It must not be given at the same time as bacteriostatic antibiotics.

Overdose (symptoms, emergency procedures, antidotes), if necessary

Clamox RTU is of a low order of toxicity and is well tolerated by the parenteral route. Apart from occasional injection site reactions, which may occur even at the recommended dose, no other adverse effects are expected from an accidental overdose.

Incompatibilities

In the absence of compatibility studies, this veterinary medicinal product should not be mixed with other veterinary medicinal products.

 

PRESENTATION/PACKAGE

Vials of 50 ml, 100 ml, 250 ml and 500 ml.


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